Unisedil

Unisedil Brand names, Unisedil Analogs

Unisedil Brand Names Mixture

No information avaliable

Unisedil Chemical_Formula

C₁₆H₁₃ClN₂O

Unisedil RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Unisedil fda sheet

Unisedil msds (material safety sheet)

Unisedil MSDS

Unisedil Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Unisedil Molecular Weight

284.74 g/mol

Unisedil Melting Point

125-126^oC

Unisedil H₂O Solubility

Slightly soluble (50 mg/L)

Unisedil State

solid

Unisedil LogP

2.988

Unisedil Dosage Forms

Tablets; Injectable solution

Unisedil Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Unisedil Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Unisedil Absorption

Essentially complete, with a bioavailability of 93%.

Unisedil side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Unisedil Patient Information

Unisedil Organisms Affected

Humans and other mammals