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Paxate Brand names, Paxate Analogs

Paxate Brand Names Mixture

  • No information avaliable

Paxate Chemical_Formula


Paxate RX_link

Paxate fda sheet

Paxate msds (material safety sheet)

Paxate MSDS

Paxate Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Paxate Molecular Weight

284.74 g/mol

Paxate Melting Point


Paxate H2O Solubility

Slightly soluble (50 mg/L)

Paxate State


Paxate LogP


Paxate Dosage Forms

Tablets; Injectable solution

Paxate Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Paxate Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Paxate Absorption

Essentially complete, with a bioavailability of 93%.

Paxate side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Paxate Patient Information

Paxate Organisms Affected

Humans and other mammals