Frustan

Frustan Brand names, Frustan Analogs

Frustan Brand Names Mixture

No information avaliable

Frustan Chemical_Formula

C₁₆H₁₃ClN₂O

Frustan RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Frustan fda sheet

Frustan msds (material safety sheet)

Frustan MSDS

Frustan Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Frustan Molecular Weight

284.74 g/mol

Frustan Melting Point

125-126^oC

Frustan H₂O Solubility

Slightly soluble (50 mg/L)

Frustan State

solid

Frustan LogP

2.988

Frustan Dosage Forms

Tablets; Injectable solution

Frustan Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Frustan Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Frustan Absorption

Essentially complete, with a bioavailability of 93%.

Frustan side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Frustan Patient Information

Frustan Organisms Affected

Humans and other mammals