Valium

Valium Brand names, Valium Analogs

Valium Brand Names Mixture

No information avaliable

Valium Chemical_Formula

C₁₆H₁₃ClN₂O

Valium RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Valium fda sheet

Valium msds (material safety sheet)

Valium MSDS

Valium Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Valium Molecular Weight

284.74 g/mol

Valium Melting Point

125-126^oC

Valium H₂O Solubility

Slightly soluble (50 mg/L)

Valium State

solid

Valium LogP

2.988

Valium Dosage Forms

Tablets; Injectable solution

Valium Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Valium Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Valium Absorption

Essentially complete, with a bioavailability of 93%.

Valium side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Valium Patient Information

Valium Organisms Affected

Humans and other mammals