Calmpose

Calmpose Brand names, Calmpose Analogs

Calmpose Brand Names Mixture

No information avaliable

Calmpose Chemical_Formula

C₁₆H₁₃ClN₂O

Calmpose RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Calmpose fda sheet

Calmpose msds (material safety sheet)

Calmpose MSDS

Calmpose Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Calmpose Molecular Weight

284.74 g/mol

Calmpose Melting Point

125-126^oC

Calmpose H₂O Solubility

Slightly soluble (50 mg/L)

Calmpose State

solid

Calmpose LogP

2.988

Calmpose Dosage Forms

Tablets; Injectable solution

Calmpose Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Calmpose Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Calmpose Absorption

Essentially complete, with a bioavailability of 93%.

Calmpose side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Calmpose Patient Information

Calmpose Organisms Affected

Humans and other mammals