Vatran

Vatran Brand names, Vatran Analogs

Vatran Brand Names Mixture

No information avaliable

Vatran Chemical_Formula

C₁₆H₁₃ClN₂O

Vatran RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Vatran fda sheet

Vatran msds (material safety sheet)

Vatran MSDS

Vatran Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Vatran Molecular Weight

284.74 g/mol

Vatran Melting Point

125-126^oC

Vatran H₂O Solubility

Slightly soluble (50 mg/L)

Vatran State

solid

Vatran LogP

2.988

Vatran Dosage Forms

Tablets; Injectable solution

Vatran Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Vatran Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Vatran Absorption

Essentially complete, with a bioavailability of 93%.

Vatran side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Vatran Patient Information

Vatran Organisms Affected

Humans and other mammals