Mandrozep

Mandrozep Brand names, Mandrozep Analogs

Mandrozep Brand Names Mixture

No information avaliable

Mandrozep Chemical_Formula

C₁₆H₁₃ClN₂O

Mandrozep RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Mandrozep fda sheet

Mandrozep msds (material safety sheet)

Mandrozep MSDS

Mandrozep Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Mandrozep Molecular Weight

284.74 g/mol

Mandrozep Melting Point

125-126^oC

Mandrozep H₂O Solubility

Slightly soluble (50 mg/L)

Mandrozep State

solid

Mandrozep LogP

2.988

Mandrozep Dosage Forms

Tablets; Injectable solution

Mandrozep Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Mandrozep Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Mandrozep Absorption

Essentially complete, with a bioavailability of 93%.

Mandrozep side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Mandrozep Patient Information

Mandrozep Organisms Affected

Humans and other mammals