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Diacepan Brand names, Diacepan Analogs

Diacepan Brand Names Mixture

  • No information avaliable

Diacepan Chemical_Formula

C16H13ClN2O

Diacepan RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Diacepan fda sheet

Diacepan msds (material safety sheet)

Diacepan MSDS

Diacepan Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Diacepan Molecular Weight

284.74 g/mol

Diacepan Melting Point

125-126oC

Diacepan H2O Solubility

Slightly soluble (50 mg/L)

Diacepan State

solid

Diacepan LogP

2.988

Diacepan Dosage Forms

Tablets; Injectable solution

Diacepan Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Diacepan Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Diacepan Absorption

Essentially complete, with a bioavailability of 93%.

Diacepan side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Diacepan Patient Information

Diacepan Organisms Affected

Humans and other mammals