Saromet

Saromet Brand names, Saromet Analogs

Saromet Brand Names Mixture

No information avaliable

Saromet Chemical_Formula

C₁₆H₁₃ClN₂O

Saromet RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Saromet fda sheet

Saromet msds (material safety sheet)

Saromet MSDS

Saromet Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Saromet Molecular Weight

284.74 g/mol

Saromet Melting Point

125-126^oC

Saromet H₂O Solubility

Slightly soluble (50 mg/L)

Saromet State

solid

Saromet LogP

2.988

Saromet Dosage Forms

Tablets; Injectable solution

Saromet Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Saromet Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Saromet Absorption

Essentially complete, with a bioavailability of 93%.

Saromet side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Saromet Patient Information

Saromet Organisms Affected

Humans and other mammals