Paranten

Paranten Brand names, Paranten Analogs

Paranten Brand Names Mixture

No information avaliable

Paranten Chemical_Formula

C₁₆H₁₃ClN₂O

Paranten RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Paranten fda sheet

Paranten msds (material safety sheet)

Paranten MSDS

Paranten Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Paranten Molecular Weight

284.74 g/mol

Paranten Melting Point

125-126^oC

Paranten H₂O Solubility

Slightly soluble (50 mg/L)

Paranten State

solid

Paranten LogP

2.988

Paranten Dosage Forms

Tablets; Injectable solution

Paranten Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Paranten Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Paranten Absorption

Essentially complete, with a bioavailability of 93%.

Paranten side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Paranten Patient Information

Paranten Organisms Affected

Humans and other mammals