Zetran

Zetran Brand names, Zetran Analogs

Zetran Brand Names Mixture

No information avaliable

Zetran Chemical_Formula

C₁₆H₁₃ClN₂O

Zetran RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Zetran fda sheet

Zetran msds (material safety sheet)

Zetran MSDS

Zetran Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Zetran Molecular Weight

284.74 g/mol

Zetran Melting Point

125-126^oC

Zetran H₂O Solubility

Slightly soluble (50 mg/L)

Zetran State

solid

Zetran LogP

2.988

Zetran Dosage Forms

Tablets; Injectable solution

Zetran Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Zetran Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Zetran Absorption

Essentially complete, with a bioavailability of 93%.

Zetran side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Zetran Patient Information

Zetran Organisms Affected

Humans and other mammals