Solis

Solis Brand names, Solis Analogs

Solis Brand Names Mixture

No information avaliable

Solis Chemical_Formula

C₁₆H₁₃ClN₂O

Solis RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Solis fda sheet

Solis msds (material safety sheet)

Solis MSDS

Solis Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Solis Molecular Weight

284.74 g/mol

Solis Melting Point

125-126^oC

Solis H₂O Solubility

Slightly soluble (50 mg/L)

Solis State

solid

Solis LogP

2.988

Solis Dosage Forms

Tablets; Injectable solution

Solis Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Solis Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Solis Absorption

Essentially complete, with a bioavailability of 93%.

Solis side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Solis Patient Information

Solis Organisms Affected

Humans and other mammals