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Tranquirit Brand names, Tranquirit Analogs

Tranquirit Brand Names Mixture

  • No information avaliable

Tranquirit Chemical_Formula

C16H13ClN2O

Tranquirit RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Tranquirit fda sheet

Tranquirit msds (material safety sheet)

Tranquirit MSDS

Tranquirit Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Tranquirit Molecular Weight

284.74 g/mol

Tranquirit Melting Point

125-126oC

Tranquirit H2O Solubility

Slightly soluble (50 mg/L)

Tranquirit State

solid

Tranquirit LogP

2.988

Tranquirit Dosage Forms

Tablets; Injectable solution

Tranquirit Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Tranquirit Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Tranquirit Absorption

Essentially complete, with a bioavailability of 93%.

Tranquirit side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Tranquirit Patient Information

Tranquirit Organisms Affected

Humans and other mammals