Tranquase

Tranquase Brand names, Tranquase Analogs

Tranquase Brand Names Mixture

No information avaliable

Tranquase Chemical_Formula

C₁₆H₁₃ClN₂O

Tranquase RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Tranquase fda sheet

Tranquase msds (material safety sheet)

Tranquase MSDS

Tranquase Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Tranquase Molecular Weight

284.74 g/mol

Tranquase Melting Point

125-126^oC

Tranquase H₂O Solubility

Slightly soluble (50 mg/L)

Tranquase State

solid

Tranquase LogP

2.988

Tranquase Dosage Forms

Tablets; Injectable solution

Tranquase Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Tranquase Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Tranquase Absorption

Essentially complete, with a bioavailability of 93%.

Tranquase side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Tranquase Patient Information

Tranquase Organisms Affected

Humans and other mammals