Calmocitene

Calmocitene Brand names, Calmocitene Analogs

Calmocitene Brand Names Mixture

No information avaliable

Calmocitene Chemical_Formula

C₁₆H₁₃ClN₂O

Calmocitene RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Calmocitene fda sheet

Calmocitene msds (material safety sheet)

Calmocitene MSDS

Calmocitene Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Calmocitene Molecular Weight

284.74 g/mol

Calmocitene Melting Point

125-126^oC

Calmocitene H₂O Solubility

Slightly soluble (50 mg/L)

Calmocitene State

solid

Calmocitene LogP

2.988

Calmocitene Dosage Forms

Tablets; Injectable solution

Calmocitene Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Calmocitene Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Calmocitene Absorption

Essentially complete, with a bioavailability of 93%.

Calmocitene side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Calmocitene Patient Information

Calmocitene Organisms Affected

Humans and other mammals