Atilen

Atilen Brand names, Atilen Analogs

Atilen Brand Names Mixture

No information avaliable

Atilen Chemical_Formula

C₁₆H₁₃ClN₂O

Atilen RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Atilen fda sheet

Atilen msds (material safety sheet)

Atilen MSDS

Atilen Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Atilen Molecular Weight

284.74 g/mol

Atilen Melting Point

125-126^oC

Atilen H₂O Solubility

Slightly soluble (50 mg/L)

Atilen State

solid

Atilen LogP

2.988

Atilen Dosage Forms

Tablets; Injectable solution

Atilen Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Atilen Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Atilen Absorption

Essentially complete, with a bioavailability of 93%.

Atilen side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Atilen Patient Information

Atilen Organisms Affected

Humans and other mammals