Diazepam en es it fr

Diazepam Brand names, Diazepam Analogs

Diazepam Brand Names Mixture

  • No information avaliable

Diazepam Chemical_Formula

C16H13ClN2O

Diazepam RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Diazepam fda sheet

Diazepam msds (material safety sheet)

Diazepam MSDS

Diazepam Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Diazepam Molecular Weight

284.74 g/mol

Diazepam Melting Point

125-126oC

Diazepam H2O Solubility

Slightly soluble (50 mg/L)

Diazepam State

solid

Diazepam LogP

2.988

Diazepam Dosage Forms

Tablets; Injectable solution

Diazepam Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Diazepam Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Diazepam Absorption

Essentially complete, with a bioavailability of 93%.

Diazepam side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Diazepam Patient Information

Diazepam Organisms Affected

Humans and other mammals