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Vasotrate Brand names, Vasotrate Analogs

Vasotrate Brand Names Mixture

  • No information avaliable

Vasotrate Chemical_Formula

C6H9NO6

Vasotrate RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Vasotrate fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Vasotrate msds (material safety sheet)

Vasotrate MSDS

Vasotrate Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Vasotrate Molecular Weight

191.139 g/mol

Vasotrate Melting Point

88-91oC

Vasotrate H2O Solubility

1.07E+005 mg/L

Vasotrate State

Solid

Vasotrate LogP

-0.15

Vasotrate Dosage Forms

Tablet (immediate release); Tablet (extended release)

Vasotrate Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Vasotrate Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Vasotrate Absorption

100%

Vasotrate side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Vasotrate Patient Information

Vasotrate Organisms Affected

Humans and other mammals