Elantan
Brand names,
Elantan
Analogs
Elantan
Brand Names Mixture
Elantan
Chemical_Formula
C6H9NO6
Elantan
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Elantan
fda sheet
Elantan
msds (material safety sheet)
Elantan
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Elantan
Molecular Weight
191.139 g/mol
Elantan
Melting Point
88-91oC
Elantan
H2O Solubility
1.07E+005 mg/L
Elantan
State
Solid
Elantan
LogP
-0.15
Elantan
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Elantan
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Elantan
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Elantan
Absorption
100%
Elantan
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Elantan
Patient Information
Elantan
Organisms Affected
Humans and other mammals