Mono Corax Retard
Brand names,
Mono Corax Retard
Analogs
Mono Corax Retard
Brand Names Mixture
Mono Corax Retard
Chemical_Formula
C6H9NO6
Mono Corax Retard
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Mono Corax Retard
fda sheet
Mono Corax Retard
msds (material safety sheet)
Mono Corax Retard
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Mono Corax Retard
Molecular Weight
191.139 g/mol
Mono Corax Retard
Melting Point
88-91oC
Mono Corax Retard
H2O Solubility
1.07E+005 mg/L
Mono Corax Retard
State
Solid
Mono Corax Retard
LogP
-0.15
Mono Corax Retard
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Mono Corax Retard
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Mono Corax Retard
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Mono Corax Retard
Absorption
100%
Mono Corax Retard
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Mono Corax Retard
Patient Information
Mono Corax Retard
Organisms Affected
Humans and other mammals