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Edistol Brand names, Edistol Analogs

Edistol Brand Names Mixture

  • No information avaliable

Edistol Chemical_Formula

C6H9NO6

Edistol RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Edistol fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Edistol msds (material safety sheet)

Edistol MSDS

Edistol Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Edistol Molecular Weight

191.139 g/mol

Edistol Melting Point

88-91oC

Edistol H2O Solubility

1.07E+005 mg/L

Edistol State

Solid

Edistol LogP

-0.15

Edistol Dosage Forms

Tablet (immediate release); Tablet (extended release)

Edistol Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Edistol Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Edistol Absorption

100%

Edistol side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Edistol Patient Information

Edistol Organisms Affected

Humans and other mammals