PharmacyCodes



Ismn Basics en es it fr

Ismn Basics Brand names, Ismn Basics Analogs

Ismn Basics Brand Names Mixture

  • No information avaliable

Ismn Basics Chemical_Formula

C6H9NO6

Ismn Basics RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Ismn Basics fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Ismn Basics msds (material safety sheet)

Ismn_Basics MSDS

Ismn Basics Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Ismn Basics Molecular Weight

191.139 g/mol

Ismn Basics Melting Point

88-91oC

Ismn Basics H2O Solubility

1.07E+005 mg/L

Ismn Basics State

Solid

Ismn Basics LogP

-0.15

Ismn Basics Dosage Forms

Tablet (immediate release); Tablet (extended release)

Ismn Basics Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Ismn Basics Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Ismn Basics Absorption

100%

Ismn Basics side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Ismn Basics Patient Information

Ismn Basics Organisms Affected

Humans and other mammals