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Pertil Brand names, Pertil Analogs

Pertil Brand Names Mixture

  • No information avaliable

Pertil Chemical_Formula

C6H9NO6

Pertil RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Pertil fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Pertil msds (material safety sheet)

Pertil MSDS

Pertil Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Pertil Molecular Weight

191.139 g/mol

Pertil Melting Point

88-91oC

Pertil H2O Solubility

1.07E+005 mg/L

Pertil State

Solid

Pertil LogP

-0.15

Pertil Dosage Forms

Tablet (immediate release); Tablet (extended release)

Pertil Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Pertil Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Pertil Absorption

100%

Pertil side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Pertil Patient Information

Pertil Organisms Affected

Humans and other mammals