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Monotrate Brand names, Monotrate Analogs

Monotrate Brand Names Mixture

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Monotrate Chemical_Formula


Monotrate RX_link

Monotrate fda sheet

Monotrate msds (material safety sheet)

Monotrate MSDS

Monotrate Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monotrate Molecular Weight

191.139 g/mol

Monotrate Melting Point


Monotrate H2O Solubility

1.07E+005 mg/L

Monotrate State


Monotrate LogP


Monotrate Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monotrate Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monotrate Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monotrate Absorption


Monotrate side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monotrate Patient Information

Monotrate Organisms Affected

Humans and other mammals