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Monosordil Brand names, Monosordil Analogs

Monosordil Brand Names Mixture

  • No information avaliable

Monosordil Chemical_Formula

C6H9NO6

Monosordil RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Monosordil fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Monosordil msds (material safety sheet)

Monosordil MSDS

Monosordil Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monosordil Molecular Weight

191.139 g/mol

Monosordil Melting Point

88-91oC

Monosordil H2O Solubility

1.07E+005 mg/L

Monosordil State

Solid

Monosordil LogP

-0.15

Monosordil Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monosordil Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monosordil Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monosordil Absorption

100%

Monosordil side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monosordil Patient Information

Monosordil Organisms Affected

Humans and other mammals