Ismexin
Brand names,
Ismexin
Analogs
Ismexin
Brand Names Mixture
Ismexin
Chemical_Formula
C6H9NO6
Ismexin
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Ismexin
fda sheet
Ismexin
msds (material safety sheet)
Ismexin
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Ismexin
Molecular Weight
191.139 g/mol
Ismexin
Melting Point
88-91oC
Ismexin
H2O Solubility
1.07E+005 mg/L
Ismexin
State
Solid
Ismexin
LogP
-0.15
Ismexin
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Ismexin
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Ismexin
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Ismexin
Absorption
100%
Ismexin
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Ismexin
Patient Information
Ismexin
Organisms Affected
Humans and other mammals