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Mononit Brand names, Mononit Analogs

Mononit Brand Names Mixture

  • No information avaliable

Mononit Chemical_Formula

C6H9NO6

Mononit RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Mononit fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Mononit msds (material safety sheet)

Mononit MSDS

Mononit Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Mononit Molecular Weight

191.139 g/mol

Mononit Melting Point

88-91oC

Mononit H2O Solubility

1.07E+005 mg/L

Mononit State

Solid

Mononit LogP

-0.15

Mononit Dosage Forms

Tablet (immediate release); Tablet (extended release)

Mononit Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Mononit Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Mononit Absorption

100%

Mononit side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Mononit Patient Information

Mononit Organisms Affected

Humans and other mammals