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Olicardin Brand names, Olicardin Analogs

Olicardin Brand Names Mixture

  • No information avaliable

Olicardin Chemical_Formula

C6H9NO6

Olicardin RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Olicardin fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Olicardin msds (material safety sheet)

Olicardin MSDS

Olicardin Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Olicardin Molecular Weight

191.139 g/mol

Olicardin Melting Point

88-91oC

Olicardin H2O Solubility

1.07E+005 mg/L

Olicardin State

Solid

Olicardin LogP

-0.15

Olicardin Dosage Forms

Tablet (immediate release); Tablet (extended release)

Olicardin Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Olicardin Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Olicardin Absorption

100%

Olicardin side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Olicardin Patient Information

Olicardin Organisms Affected

Humans and other mammals