ISMN AL

ISMN AL Brand names, ISMN AL Analogs

ISMN AL Brand Names Mixture

No information avaliable

ISMN AL Chemical_Formula

C₆H₉NO₆

ISMN AL RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

ISMN AL fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

ISMN AL msds (material safety sheet)

ISMN_AL MSDS

ISMN AL Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

ISMN AL Molecular Weight

191.139 g/mol

ISMN AL Melting Point

88-91^oC

ISMN AL H₂O Solubility

1.07E+005 mg/L

ISMN AL State

Solid

ISMN AL LogP

-0.15

ISMN AL Dosage Forms

Tablet (immediate release); Tablet (extended release)

ISMN AL Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

ISMN AL Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

ISMN AL Absorption

100%

ISMN AL side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD₅₀=mg/kg(orally in rat)

ISMN AL Patient Information

ISMN AL Organisms Affected

Humans and other mammals