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Monosigma Brand names, Monosigma Analogs

Monosigma Brand Names Mixture

  • No information avaliable

Monosigma Chemical_Formula

C6H9NO6

Monosigma RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Monosigma fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Monosigma msds (material safety sheet)

Monosigma MSDS

Monosigma Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monosigma Molecular Weight

191.139 g/mol

Monosigma Melting Point

88-91oC

Monosigma H2O Solubility

1.07E+005 mg/L

Monosigma State

Solid

Monosigma LogP

-0.15

Monosigma Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monosigma Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monosigma Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monosigma Absorption

100%

Monosigma side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monosigma Patient Information

Monosigma Organisms Affected

Humans and other mammals