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Monosigma Brand names, Monosigma Analogs

Monosigma Brand Names Mixture

  • No information avaliable

Monosigma Chemical_Formula


Monosigma RX_link

Monosigma fda sheet

Monosigma msds (material safety sheet)

Monosigma MSDS

Monosigma Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monosigma Molecular Weight

191.139 g/mol

Monosigma Melting Point


Monosigma H2O Solubility

1.07E+005 mg/L

Monosigma State


Monosigma LogP


Monosigma Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monosigma Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monosigma Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monosigma Absorption


Monosigma side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monosigma Patient Information

Monosigma Organisms Affected

Humans and other mammals