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Monoclair Brand names, Monoclair Analogs

Monoclair Brand Names Mixture

  • No information avaliable

Monoclair Chemical_Formula

C6H9NO6

Monoclair RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Monoclair fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Monoclair msds (material safety sheet)

Monoclair MSDS

Monoclair Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monoclair Molecular Weight

191.139 g/mol

Monoclair Melting Point

88-91oC

Monoclair H2O Solubility

1.07E+005 mg/L

Monoclair State

Solid

Monoclair LogP

-0.15

Monoclair Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monoclair Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monoclair Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monoclair Absorption

100%

Monoclair side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monoclair Patient Information

Monoclair Organisms Affected

Humans and other mammals