Monolong 40
Brand names,
Monolong 40
Analogs
Monolong 40
Brand Names Mixture
Monolong 40
Chemical_Formula
C6H9NO6
Monolong 40
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Monolong 40
fda sheet
Monolong 40
msds (material safety sheet)
Monolong 40
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Monolong 40
Molecular Weight
191.139 g/mol
Monolong 40
Melting Point
88-91oC
Monolong 40
H2O Solubility
1.07E+005 mg/L
Monolong 40
State
Solid
Monolong 40
LogP
-0.15
Monolong 40
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Monolong 40
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Monolong 40
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Monolong 40
Absorption
100%
Monolong 40
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Monolong 40
Patient Information
Monolong 40
Organisms Affected
Humans and other mammals