Isopen-20

Isopen-20 Brand names, Isopen-20 Analogs

Isopen-20 Brand Names Mixture

No information avaliable

Isopen-20 Chemical_Formula

C₆H₉NO₆

Isopen-20 RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Isopen-20 fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Isopen-20 msds (material safety sheet)

Isopen-20 MSDS

Isopen-20 Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Isopen-20 Molecular Weight

191.139 g/mol

Isopen-20 Melting Point

88-91^oC

Isopen-20 H₂O Solubility

1.07E+005 mg/L

Isopen-20 State

Solid

Isopen-20 LogP

-0.15

Isopen-20 Dosage Forms

Tablet (immediate release); Tablet (extended release)

Isopen-20 Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Isopen-20 Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Isopen-20 Absorption

100%

Isopen-20 side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD₅₀=mg/kg(orally in rat)

Isopen-20 Patient Information

Isopen-20 Organisms Affected

Humans and other mammals