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Monisid Brand names, Monisid Analogs

Monisid Brand Names Mixture

  • No information avaliable

Monisid Chemical_Formula

C6H9NO6

Monisid RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Monisid fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Monisid msds (material safety sheet)

Monisid MSDS

Monisid Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monisid Molecular Weight

191.139 g/mol

Monisid Melting Point

88-91oC

Monisid H2O Solubility

1.07E+005 mg/L

Monisid State

Solid

Monisid LogP

-0.15

Monisid Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monisid Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monisid Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monisid Absorption

100%

Monisid side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monisid Patient Information

Monisid Organisms Affected

Humans and other mammals