Elantan Long
Brand names,
Elantan Long
Analogs
Elantan Long
Brand Names Mixture
Elantan Long
Chemical_Formula
C6H9NO6
Elantan Long
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Elantan Long
fda sheet
Elantan Long
msds (material safety sheet)
Elantan Long
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Elantan Long
Molecular Weight
191.139 g/mol
Elantan Long
Melting Point
88-91oC
Elantan Long
H2O Solubility
1.07E+005 mg/L
Elantan Long
State
Solid
Elantan Long
LogP
-0.15
Elantan Long
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Elantan Long
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Elantan Long
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Elantan Long
Absorption
100%
Elantan Long
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Elantan Long
Patient Information
Elantan Long
Organisms Affected
Humans and other mammals