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Imtrate Brand names, Imtrate Analogs

Imtrate Brand Names Mixture

  • No information avaliable

Imtrate Chemical_Formula

C6H9NO6

Imtrate RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Imtrate fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Imtrate msds (material safety sheet)

Imtrate MSDS

Imtrate Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Imtrate Molecular Weight

191.139 g/mol

Imtrate Melting Point

88-91oC

Imtrate H2O Solubility

1.07E+005 mg/L

Imtrate State

Solid

Imtrate LogP

-0.15

Imtrate Dosage Forms

Tablet (immediate release); Tablet (extended release)

Imtrate Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Imtrate Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Imtrate Absorption

100%

Imtrate side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Imtrate Patient Information

Imtrate Organisms Affected

Humans and other mammals