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Orasorbil Brand names, Orasorbil Analogs

Orasorbil Brand Names Mixture

  • No information avaliable

Orasorbil Chemical_Formula

C6H9NO6

Orasorbil RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Orasorbil fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Orasorbil msds (material safety sheet)

Orasorbil MSDS

Orasorbil Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Orasorbil Molecular Weight

191.139 g/mol

Orasorbil Melting Point

88-91oC

Orasorbil H2O Solubility

1.07E+005 mg/L

Orasorbil State

Solid

Orasorbil LogP

-0.15

Orasorbil Dosage Forms

Tablet (immediate release); Tablet (extended release)

Orasorbil Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Orasorbil Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Orasorbil Absorption

100%

Orasorbil side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Orasorbil Patient Information

Orasorbil Organisms Affected

Humans and other mammals