Monosorbitrate en es it fr

Monosorbitrate Brand names, Monosorbitrate Analogs

Monosorbitrate Brand Names Mixture

  • No information avaliable

Monosorbitrate Chemical_Formula

C6H9NO6

Monosorbitrate RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Monosorbitrate fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Monosorbitrate msds (material safety sheet)

Monosorbitrate MSDS

Monosorbitrate Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monosorbitrate Molecular Weight

191.139 g/mol

Monosorbitrate Melting Point

88-91oC

Monosorbitrate H2O Solubility

1.07E+005 mg/L

Monosorbitrate State

Solid

Monosorbitrate LogP

-0.15

Monosorbitrate Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monosorbitrate Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monosorbitrate Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monosorbitrate Absorption

100%

Monosorbitrate side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monosorbitrate Patient Information

Monosorbitrate Organisms Affected

Humans and other mammals