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Monosorbitrate Brand names, Monosorbitrate Analogs

Monosorbitrate Brand Names Mixture

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Monosorbitrate Chemical_Formula


Monosorbitrate RX_link

Monosorbitrate fda sheet

Monosorbitrate msds (material safety sheet)

Monosorbitrate MSDS

Monosorbitrate Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monosorbitrate Molecular Weight

191.139 g/mol

Monosorbitrate Melting Point


Monosorbitrate H2O Solubility

1.07E+005 mg/L

Monosorbitrate State


Monosorbitrate LogP


Monosorbitrate Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monosorbitrate Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monosorbitrate Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monosorbitrate Absorption


Monosorbitrate side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monosorbitrate Patient Information

Monosorbitrate Organisms Affected

Humans and other mammals