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Monoket Brand names, Monoket Analogs

Monoket Brand Names Mixture

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Monoket Chemical_Formula


Monoket RX_link

Monoket fda sheet

Monoket msds (material safety sheet)

Monoket MSDS

Monoket Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monoket Molecular Weight

191.139 g/mol

Monoket Melting Point


Monoket H2O Solubility

1.07E+005 mg/L

Monoket State


Monoket LogP


Monoket Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monoket Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monoket Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monoket Absorption


Monoket side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monoket Patient Information

Monoket Organisms Affected

Humans and other mammals