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Uniket Brand names, Uniket Analogs

Uniket Brand Names Mixture

  • No information avaliable

Uniket Chemical_Formula

C6H9NO6

Uniket RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Uniket fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Uniket msds (material safety sheet)

Uniket MSDS

Uniket Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Uniket Molecular Weight

191.139 g/mol

Uniket Melting Point

88-91oC

Uniket H2O Solubility

1.07E+005 mg/L

Uniket State

Solid

Uniket LogP

-0.15

Uniket Dosage Forms

Tablet (immediate release); Tablet (extended release)

Uniket Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Uniket Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Uniket Absorption

100%

Uniket side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Uniket Patient Information

Uniket Organisms Affected

Humans and other mammals