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Sigacora Brand names, Sigacora Analogs

Sigacora Brand Names Mixture

  • No information avaliable

Sigacora Chemical_Formula

C6H9NO6

Sigacora RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Sigacora fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Sigacora msds (material safety sheet)

Sigacora MSDS

Sigacora Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Sigacora Molecular Weight

191.139 g/mol

Sigacora Melting Point

88-91oC

Sigacora H2O Solubility

1.07E+005 mg/L

Sigacora State

Solid

Sigacora LogP

-0.15

Sigacora Dosage Forms

Tablet (immediate release); Tablet (extended release)

Sigacora Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Sigacora Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Sigacora Absorption

100%

Sigacora side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Sigacora Patient Information

Sigacora Organisms Affected

Humans and other mammals