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Plodin Brand names, Plodin Analogs

Plodin Brand Names Mixture

  • No information avaliable

Plodin Chemical_Formula

C6H9NO6

Plodin RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Plodin fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Plodin msds (material safety sheet)

Plodin MSDS

Plodin Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Plodin Molecular Weight

191.139 g/mol

Plodin Melting Point

88-91oC

Plodin H2O Solubility

1.07E+005 mg/L

Plodin State

Solid

Plodin LogP

-0.15

Plodin Dosage Forms

Tablet (immediate release); Tablet (extended release)

Plodin Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Plodin Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Plodin Absorption

100%

Plodin side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Plodin Patient Information

Plodin Organisms Affected

Humans and other mammals