ISMN en es it fr

ISMN Brand names, ISMN Analogs

ISMN Brand Names Mixture

  • No information avaliable

ISMN Chemical_Formula

C6H9NO6

ISMN RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

ISMN fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

ISMN msds (material safety sheet)

ISMN MSDS

ISMN Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

ISMN Molecular Weight

191.139 g/mol

ISMN Melting Point

88-91oC

ISMN H2O Solubility

1.07E+005 mg/L

ISMN State

Solid

ISMN LogP

-0.15

ISMN Dosage Forms

Tablet (immediate release); Tablet (extended release)

ISMN Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

ISMN Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

ISMN Absorption

100%

ISMN side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

ISMN Patient Information

ISMN Organisms Affected

Humans and other mammals