Imazin
Brand names,
Imazin
Analogs
Imazin
Brand Names Mixture
Imazin
Chemical_Formula
C6H9NO6
Imazin
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Imazin
fda sheet
Imazin
msds (material safety sheet)
Imazin
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Imazin
Molecular Weight
191.139 g/mol
Imazin
Melting Point
88-91oC
Imazin
H2O Solubility
1.07E+005 mg/L
Imazin
State
Solid
Imazin
LogP
-0.15
Imazin
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Imazin
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Imazin
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Imazin
Absorption
100%
Imazin
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Imazin
Patient Information
Imazin
Organisms Affected
Humans and other mammals