Monocord 50 Sr
Brand names,
Monocord 50 Sr
Analogs
Monocord 50 Sr
Brand Names Mixture
Monocord 50 Sr
Chemical_Formula
C6H9NO6
Monocord 50 Sr
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Monocord 50 Sr
fda sheet
Monocord 50 Sr
msds (material safety sheet)
Monocord 50 Sr
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Monocord 50 Sr
Molecular Weight
191.139 g/mol
Monocord 50 Sr
Melting Point
88-91oC
Monocord 50 Sr
H2O Solubility
1.07E+005 mg/L
Monocord 50 Sr
State
Solid
Monocord 50 Sr
LogP
-0.15
Monocord 50 Sr
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Monocord 50 Sr
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Monocord 50 Sr
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Monocord 50 Sr
Absorption
100%
Monocord 50 Sr
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Monocord 50 Sr
Patient Information
Monocord 50 Sr
Organisms Affected
Humans and other mammals