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Monizid Brand names, Monizid Analogs

Monizid Brand Names Mixture

  • No information avaliable

Monizid Chemical_Formula

C6H9NO6

Monizid RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Monizid fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Monizid msds (material safety sheet)

Monizid MSDS

Monizid Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monizid Molecular Weight

191.139 g/mol

Monizid Melting Point

88-91oC

Monizid H2O Solubility

1.07E+005 mg/L

Monizid State

Solid

Monizid LogP

-0.15

Monizid Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monizid Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monizid Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monizid Absorption

100%

Monizid side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monizid Patient Information

Monizid Organisms Affected

Humans and other mammals