PharmacyCodes



IS 5MN en es it fr

IS 5MN Brand names, IS 5MN Analogs

IS 5MN Brand Names Mixture

  • No information avaliable

IS 5MN Chemical_Formula

C6H9NO6

IS 5MN RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

IS 5MN fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

IS 5MN msds (material safety sheet)

IS_5MN MSDS

IS 5MN Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

IS 5MN Molecular Weight

191.139 g/mol

IS 5MN Melting Point

88-91oC

IS 5MN H2O Solubility

1.07E+005 mg/L

IS 5MN State

Solid

IS 5MN LogP

-0.15

IS 5MN Dosage Forms

Tablet (immediate release); Tablet (extended release)

IS 5MN Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

IS 5MN Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

IS 5MN Absorption

100%

IS 5MN side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

IS 5MN Patient Information

IS 5MN Organisms Affected

Humans and other mammals