Corangin Sr
Brand names,
Corangin Sr
Analogs
Corangin Sr
Brand Names Mixture
Corangin Sr
Chemical_Formula
C6H9NO6
Corangin Sr
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Corangin Sr
fda sheet
Corangin Sr
msds (material safety sheet)
Corangin Sr
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Corangin Sr
Molecular Weight
191.139 g/mol
Corangin Sr
Melting Point
88-91oC
Corangin Sr
H2O Solubility
1.07E+005 mg/L
Corangin Sr
State
Solid
Corangin Sr
LogP
-0.15
Corangin Sr
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Corangin Sr
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Corangin Sr
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Corangin Sr
Absorption
100%
Corangin Sr
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Corangin Sr
Patient Information
Corangin Sr
Organisms Affected
Humans and other mammals