Monis en es it fr

Monis Brand names, Monis Analogs

Monis Brand Names Mixture

  • No information avaliable

Monis Chemical_Formula

C6H9NO6

Monis RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Monis fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Monis msds (material safety sheet)

Monis MSDS

Monis Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Monis Molecular Weight

191.139 g/mol

Monis Melting Point

88-91oC

Monis H2O Solubility

1.07E+005 mg/L

Monis State

Solid

Monis LogP

-0.15

Monis Dosage Forms

Tablet (immediate release); Tablet (extended release)

Monis Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Monis Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Monis Absorption

100%

Monis side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Monis Patient Information

Monis Organisms Affected

Humans and other mammals