Monolong 60
Brand names,
Monolong 60
Analogs
Monolong 60
Brand Names Mixture
Monolong 60
Chemical_Formula
C6H9NO6
Monolong 60
RX_link
http://www.rxlist.com/cgi/generic/isomono2.htm
Monolong 60
fda sheet
Monolong 60
msds (material safety sheet)
Monolong 60
Synthesis Reference
Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)
Monolong 60
Molecular Weight
191.139 g/mol
Monolong 60
Melting Point
88-91oC
Monolong 60
H2O Solubility
1.07E+005 mg/L
Monolong 60
State
Solid
Monolong 60
LogP
-0.15
Monolong 60
Dosage Forms
Tablet (immediate release); Tablet (extended release)
Monolong 60
Indication
For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
Monolong 60
Pharmacology
Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.
Monolong 60
Absorption
100%
Monolong 60
side effects and Toxicity
Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)
Monolong 60
Patient Information
Monolong 60
Organisms Affected
Humans and other mammals